Osteoporosis can make the bones weak and brittle. Sometimes, the bones are so brittle that mild stress or a fall like coughing or bending over might result in a fracture. Typically, osteoporosis-related fractures occur in the spine, wrist, and hip. Bone is a living tissue that constantly breaks and replaces itself. Osteoporosis occurs when the new bone creation fails to keep up with the loss of old bone. There can be different causes of osteoporosis, but some health conditions increase the risk. Inflammatory bowel disease Several studies reveal that patients with inflammatory bowel disease (IBD), predominantly Crohn’s disease, are more susceptible to developing osteopenia and osteoporosis. Studies suggest that osteoporosis might occur in every one in seven people with Crohn’s Disease. However, there is no one specific reason for IBB being responsible for osteoporosis. But some plausible explanations include: Prednisone, a corticosteroid for IBD treatment, impacts bone metabolism. In only a few months of consumption, it decreases bone density and heightens the susceptibility to fracture. Sadly, even low prednisone dosage can increase the risk of fractures. Alternative options like methotrexate and cyclosporine can also lower bone density. Crohn’s disease, or IBD, is a known risk factor for osteoporosis. Many newly diagnosed patients showed low bone densities even before they started corticosteroids.