Hereditary angioedema (HAE) is a rare genetic condition that can affect different parts of the body and cause swelling under the skin, including the lining of the gut and the lungs. This condition is hereditary, and there is no definitive cure for it. However, there are treatment methods that help keep the symptoms at bay. Here are some of the symptoms to look out for and treatment options. Signs and symptoms Before the onset of the condition, some signs and symptoms can be noticed and are clearly visible. It usually begins with a tingling sensation in the affected body part and is often accompanied by non-itchy rashes. The affected area then swells, and if left untreated, the swelling may increase on the first day and gradually subside over the next two to three days. It is also possible that the swelling starts in one location and then migrates to another location. Skin-related symptoms When swelling on the skin occurs, it is called subcutaneous swelling, which usually affects the hands, feet, face, and genitals. This type of swelling is also usually accompanied by redness. Unlike other types of swelling, this type does not cause itching. Often, this type of symptom is misdiagnosed as an allergic reaction, and the wrong treatment options are administered, which do not work.